What is HHCH and what are its effects and risks? Expedition to the "lost" compound

A sunset view of the cannabis plant, discovering what HHCH is
A sunset view of the cannabis plant, discovering what HHCH is

   

   

What is HHCH? First steps into the laboratory

This time we'll start right in the science labs. As early as 1942, the American chemist Roger Adams first synthesised hexahydrocannabidihexol (HHCH) and stated in his scientific study that it was more potent than the pentyl and heptyl homologue or unsaturated analogue of tetrahydrocannabinol (THC).

In the laboratory, where science meets nature, HHCH is produced by hydrogenating a distillate of tetrahydrocannabishexol (THCH) and converting it to HHCH. Hexahydrocanabihexol takes the form of a thick, high-viscosity oil.

However, unlike other minor cannabinoids, which are mostly (semi-)synthetically produced, such as THCB, THCP, THCH or THCJD, HHCH is not found in cannabis. It is a semi-synthetic cannabinoid derivative consisting of 2 different stereoisomers, i.e. the 9(R)-HHCH and 9(S)-HHCH molecules, similar to the hydrogenated compounds HHC and H4CBD.

The ratio of 9(R) to 9(S) molecules influences the potency and strength of the product, as evidenced by a 2023 study. If the product is dominated by the 9(R)-HCH isomer, the product will be more potent. A 1:1 ratio of molecules is usually used.

 

Chemical production, extraction machine for cannabis processing

Strong effects of HHCH or a route exclusively for experienced adventurers

According to effects research conducted by Roger Adams, HHCH appears to be the alpha male of the cannabis empire. It can be assumed that HHCH exerts a significant psychoactive effect on the body. Even in remote areas it is said to be 10-15 times stronger than THC and to be slightly superior to THC in its effects. But beware, there is currently no research to confirm this assumption.

Adventurers who have encountered HHCH report that it can affect perception, induce feelings of euphoria or relaxation, and relieve symptoms of pain and inflammation.

HHCH has psychoactive effects similar to those of THC. Compared to HHCP, it has slightly milder effects and lasts longer compared to HHC. The effects of HHCH can last from 2 to 8 hours.

HHCH is definitely not for the inexperienced adventurer, as it is a semi-synthetic cannabinoid that can surpass in potency any natural cannabinoid we have ever come across. This compound requires caution and respect. After use, it is definitely not recommended to drive a buggy or operate any other machinery.

Warning: you are entering the territory of potent semi-synthetic cannabinoids

As we make our way through the jungle, we must be wary of the potential pitfalls that lurk behind every bush. Like exotic insect bites, the side effects of HHCH can be treacherous.

The jungle of new compounds is not well explored and, in general, semi-synthetic cannabinoids can be much more potent than natural ones, increasing the potential risk of intoxication and overdose. Some may experience paranoia that they are being attacked by a pack of hungry crocodiles, hallucinate, experience anxiety or panic.

Possible other side effects:

  • Increased heart rate
  • Fatigue and drowsiness
  • Dry mouth
  • Redness of the eyes
  • Headaches
  • Nausea (vomiting)

Other, as yet undiscovered, side effects cannot be excluded.

Laboratory analysis or navigation in the jungle

When an adventurer decides to purchase HHCH products, they should always request a third-party lab analysis that includes key information about the purity and composition of the product.

Laboratory analysis is an essential map to safely navigate the cannabis forest, i.e. to discover the purity and composition of products and avoid potential toxic pitfalls (heavy metals, solvents, pesticides).

 

A scientist examines a cannabis plant in a field at sunset

Last camping: HHCH products

Although HHCH is not sufficiently explored, products are already appearing on the cannabis market, most notably:

  • HHCH vapes, replacement cartridges and liquids (liquids for vaporisation)
  • HHCH oil
  • Distillate
  • Extracts and concentrates
  • Hash
  • Flowers (flowers of technical hemp infused with HHCH distillate)

Caution above all

Hexahydrocannabihexol is a semi-synthetic cannabinoid derivative, produced by hydrogenation of THCH distillate and its conversion to HHCH. It exerts a strong psychoactive effect on the body, with the effects and potency of the product being influenced by the ratio of 9(R)-HCH to 9(S)-HCH molecules in the product.

 Anyone who decides to venture into the territory of semi-synthetic cannabinoids should consider all the risks before buying, as this is no ordinary expedition. Do not underestimate the power of this cannabinoid and do not overestimate your experience. Also, be careful that your fascination with this wild new drug does not lead you into risky situations. Just as in the jungle, where every step can mean an encounter with a jaguar, in the world of semi-synthetic cannabinoids you need to be cautious and respect the rules of exploring unfamiliar territory.

Make sure you have reliable equipment before embarking on your adventure - only buy from reputable retailers who have their products tested by an independent laboratory.

   

Author: Canntropy 🌴


 

Photo: Shutterstock

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